Research

«I see that there is only one way left to save them, that is, by healing them.

The task is immense, but so is the Hope»

Prof. Jérôme Lejeune

Our Research

The International Chair of Bioethics Jérôme Lejeune develops research in Bioethics with the fundamental purpose of defending the human dignity of every person from conception to natural death. It provides thoughts and arguments from an interdisciplinary perspective (scientific, ethical and legal) together with a realistic philosophy from an ontologically based personalism. We want to offer society elements to form consciences and to be able to adequately address the challenges presented by the scientific-technological developments, all this with a special and attentive eye towards the care of people with intellectual disabilities.

The areas of development of research in Bioethics are:

Fundamentals of Bioethics: person, dignity, human nature (Handbook of Fundamentals of Bioethics, Anthropology and Fundamental Ethics).
Research on Bioethics and the Beginning of Human Life: status of the human embryo, IVF, cloning, CRISPR, surrogacy (Handbook of Bioethics and the Beginning of Human Life).
Research on Biolaw: National and European legislation on current challenges in Bioethics (Handbook of Biolaw).
Research on Bioethics and End of Human Life: euthanasia, palliative care, brain death (Handbook on Bioethics and End of Human Life).
Research on emerging bioethical issues: ectogenesis, neuroethics, hybrids and interspecies chimeras, etc. (Handbook in progress) .
Studies on bioethical issues and preparation of ad hoc reports.

1. Report on surrogacy.
2. Report on non-invasive prenatal diagnosis.
3. Report on euthanasia.
4. Articles on clinical cases that have occurred in our surroundings (e.g. Alfie Evans).
5. Articles and comments on national and international regulations: critical note on euthanasia law in Spain, critical note on the approval of the right to abortion as a human right in France.

Jacques Suaudeau Prize for research in Bioethics.
Research projects:
- COMDIDOWN Project: research project on the communication of Down Syndrome diagnosis.

International Scientific Committee

Barbara Bardoni, PhD, Research Director, INSERM Institut de Pharmacologie Moléculaire et Cellulaire (IPMC), Valbonne, France.
Yann Hérault, PhD, Research Director, CNRS Honorary Chair, Scientific Advisory Board of the Jerome Lejeune Foundation, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), University of Strasbourg, and Institut Clinique de la Souris (ICS), Illkirch, France.
Marie-Claude Potier, PharmD, PhD, Research Director, CNRS Honorary Chair, Scientific Advisory Board of the Jerome Lejeune Foundation, Institut du Cerveau et de la Moelle épinière (ICM), Pitié-Salpêtrière Hospital, Paris, France.
Jacques S. Beckmann, Prof., PhD, Honorary Professor, University of Lausanne, Lausanne, Switzerland.
Bice Chini, MD, PhD, Institute of Neuroscience, National Research Council (CNR), Rome, Italy.
Cécile Cieuta-Walti, MD, University of Sherbrooke, Sherbrooke, Québec, Canada.
Aurore Curie, MD, PhD, MCU-PH, Hôpital Femme Mère Enfant, Hospices Civils de Lyon, Institut des Sciences
Cognitives Marc Jeannerod, Bron, France.
Jean-Maurice Delabar, PhD, Research Director, CNRS, Institut du Cerveau et de la Moelle épinière
(ICM), Pitié-Salpêtrière Hospital, Paris, France.
Caroline Demily, MD, PU-PH, GenoPsy, Le Vinatier Hospital, Bron, France.
Maëva Dupuis-Deniaud, MD, STAT Consulting, Lyon, France.
Juan Fortea Ormaechea, MD, PhD, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Mario Gomes-Pereira, PhD, Research Scientist, INSERM Institut de Myologie, Sorbonne University, Paris,
France.
Jean-Louis Guéant, MD, PhD, PU-PH, Research Director, INSERM Nutrition, Genetics and Environmental Risk Exposure (NGERE), University of Lorraine, Vandoeuvre-les-Nancy, France.
Stéphane Martin, PhD, Research Scientist, INSERM Institut de Pharmacologie Moléculaire et Cellulaire (IPMC), Valbonne, France.
Andre Mégarbané, MD, PhD, Institut Jérôme Lejeune, CRB BioJeL, Paris, France.
Clotilde Mircher, MD, Institut Jérôme Lejeune, Paris, France.
Hervé Moine, PhD, Research Director, CNRS, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Illkirch, France.
Françoise Muscatelli, PhD, Research Director, CNRS, Institut de Neurobiologie de la Méditerranée (Inmed), Marseille, France.
Juan Narbona García, MD, Clinical University of Navarra, Pamplona, Spain.
Aimé Ravel, MD, Institut Jérôme Lejeune, Paris, France.
Agnès Rötig, PhD, Research Director, INSERM, Institut Imagine, Paris, France.
Damien Sanlaville, MD, PU-PH, Hospices Civils de Lyon, Bron, France.
Daniel Satgé, MD, ONCODEFI and Institute for Clinical Research, Montpellier, France.
Ignacio Sfaello, MD, Infanto-Juvenile Neurology Institute, CETES, Córdoba, Argentina.
Pierre-Marie Sinet, MD, Research Director, CNRS, Paris, France.
Michèle Studer, PhD, Research Director, INSERM Institut de Biologie Valrose (iBV), Nice, France.
Enrico Tongiorgi, PhD, Prof., University of Trieste, Trieste, Italy.

Research Ethics Committee

President: Prof. Dr. Mónica López Barahona

Vice President: Prof. Dr. Nicolás Jouve de la Barreda

Secretary: Doña Rafaela de la Brena

Vocal: Prof. Dr. Sagrario Crespo

Vocal: Prof. Dr. Natalia Ochoa

Vocal: Prof. Dr. Elena Postigo

Research Programs

Beca predoctoral

Biomarcadores morfológicos no invasivos para mejorar el pronóstico y el pronóstico de la demencia temprana en el síndrome de Down

Beca predoctoral

Estudio de las vías neurohumorales (sistema renina-angiotensina-aldosterona, vía de la neprilisina y factor de crecimiento neural) en adultos con síndrome de Down, y optimización del manejo clínico de su riesgo vascular

Beca predoctoral

Contribución del silenciamiento de SNX27 en las respuestas inmunes inflamatorias y su impacto en las patologías asociadas al Síndrome de Down

Beca predoctoral

Abordajes preclínicos en el tratamiento del Síndrome de Down

Beca predoctoral

Mecanismos moleculares que protegen a las personas con síndrome de Down de desarrollar la mayoría de los tumores sólidos.

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Research

Our Research

2.500.000€

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International Scientific Committee

Research Ethics Committee

Research Programs

Biomarcadores morfológicos no invasivos para mejorar el pronóstico y el pronóstico de la demencia temprana en el síndrome de Down

Estudio de las vías neurohumorales (sistema renina-angiotensina-aldosterona, vía de la neprilisina y factor de crecimiento neural) en adultos con síndrome de Down, y optimización del manejo clínico de su riesgo vascular

Contribución del silenciamiento de SNX27 en las respuestas inmunes inflamatorias y su impacto en las patologías asociadas al Síndrome de Down

Abordajes preclínicos en el tratamiento del Síndrome de Down

Mecanismos moleculares que protegen a las personas con síndrome de Down de desarrollar la mayoría de los tumores sólidos.